Weight first, because it is half the cost
Grams per square metre measures how much cotton is in the fabric. It does not measure quality, and a 200gsm shirt from one mill can feel better than a 230gsm from another — but it does predict cost, drape and how a shirt behaves in heat.
The practical bands: 160–180gsm promotional, 200–230gsm retail standard, 240–280gsm premium and streetwear, 300gsm+ statement pieces.
Yarn second, because it changes the hand
Carded yarn keeps short fibres; combed yarn removes them. Combed is smoother, stronger and pills less, and costs 8–15% more on the blank.
Ring-spun versus open-end is a separate question about how the yarn is twisted. Ring-spun is smoother and finer; open-end is faster and coarser. A shirt can be combed and open-end, which is why "combed cotton" on a label tells you less than it appears to.
- Carded: rougher, cheaper, pills sooner.
- Combed: smoother, stronger, +8–15%.
- Ring-spun: finer surface, better for fine print detail.
- Open-end: coarser, cheaper, fine for giveaways.
Knit third, because it changes the shape
Single jersey is the standard t-shirt knit: thin, stretchy, drapes. Interlock is denser and smoother on both sides, holds shape better, and is more expensive.
Tubular versus side-seamed is a construction choice, not a knit: a tubular body has no side seams and is cheaper, with a slightly different fit through the waist.
Then check the things that are not on the label
Shrinkage, colour fastness and neck rib recovery decide whether the shirt survives three washes. None of them appear in a spec sheet you will be sent, and all of them appear in a wash test you can do yourself.
Wash the sample twice at 40°C, measure again, and look at the neck. That fifteen-minute test tells you more than any fabric description.